Randi Hutter Epstein's new book is Aroused: The History of Hormones and How They Control Just About Everything. From the transcript of her interview with NPR's Lulu Garcia-Navarro:GARCIA-NAVARRO: The book is organized around stories from key moments in hormone research. And I have to say, many of the studies they were doing in the early days were pretty gruesome.Visit Randi Hutter Epstein's website and Psychology Today blog, Birth, Babies, and Beyond.
EPSTEIN: When we say study, we tend now to think of the randomised clinical controlled trial. You know, you have one sample here. You compare it to another. When they were doing studies, they were doing sort of weird experiments on people and dogs and all kind of things. So there was Harvey Cushing. He was one of the first people to talk about that pituitary tumors can really muck you up and like send a lot of hormones awry. But here's what he tried to do that didn't work out that's kind of a wacky experiment. He had a 48-year-old man that had a pituitary tumor that was making him have double vision and headaches and other endocrine issues. And Harvey Cushing thought, what if we take a nice, healthy pituitary of a baby that just died if there is a newborn that didn't make it and just implant that in this old man, and then we just revive him and he'd be back to normal. Newspapers got a hold of it, as media tends to do. And there were wonderful headlines like baby brain, you know, broken brain fixed by baby. And it went wild in terms of, wow, we can now cure broken, old brains. And, spoiler alert, let's just say that we don't replace baby pituitary glands into grownups when they have pituitary tumors anymore.
GARCIA-NAVARRO: Some of what these scientists were doing, though, was actually helping people. And you tell the story of a short 7-year-old called Jeffrey Balaban.
EPSTEIN: Yes. There was this huge optimism started in the 1920s when we figured out that insulin can help diabetics. So the thinking was, if we can change diabetes - which was a deadly disease - to a chronic illness, what else can we do? So originally the thought was, let's get growth hormone from cows just the way we got insulin from cows, and we'll give it to short kids. So...[read on]
Writers Read: Randi Hutter Epstein (September 2010).
Coffee with a Canine: Randi Hutter Epstein, Ellie and Dexter.
--Marshal Zeringue